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行业动态 | Industry News — February 18, 2026

🔬 行业动态 — 2026年2月18日 Compiled by Lumina Research · 亮眼科学 🏥 FDA 审批与临床进展 / FDA Approvals & Clinical Updates 1. FDA 批准 Keytruda 联合方案用于铂耐药卵巢癌 FDA Approves Pembrolizumab Combo for Platinum-Resistant Ovarian Cancer 2月10日,FDA 批准 pembrolizumab(Keytruda)联合紫杉醇(±贝伐珠单抗)用于 PD-L1 阳性铂耐药复发性卵巢癌/输卵管癌/原发性腹膜癌。基于 KEYNOTE-B96 III 期试验数据,PFS 风险降低 30%(HR 0.70),OS
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paper-radar

Paper Radar | February 18, 2026

📡 Paper Radar — 2026年2月18日 Curated by Lumina Research · 亮眼科学 Nature Immunology Single-cell multiomic atlas of healthy pediatric bone marrow reveals age-dependent differences in lineage differentiation driven by stromal signaling 儿童健康骨髓的多模态单细胞图谱,揭示从婴儿期到成年期造血干细胞分化的年龄依赖性差异,由基质信号驱动。这是理解儿童血液肿瘤发生的重要基础资源。 🔗 Nature Immunology Nature Cancer M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors M-PACT
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paper-radar

Paper Radar | February 17, 2026

📡 Paper Radar — 2026年2月17日 Curated by Lumina Research · 亮眼科学 Nature Immunology Single-cell multiomic atlas of healthy pediatric bone marrow reveals age-dependent differences in lineage differentiation driven by stromal signaling Belderbos 团队构建了覆盖婴儿期、青少年期和成年期的人类健康骨髓多模态单细胞图谱,揭示基质信号驱动的谱系分化年龄依赖性差异。 🔗 Nature Immunology Nature Cancer M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors Smith
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paper-radar

Paper Radar | February 16, 2026

📡 Paper Radar — 2026年2月16日 Curated by Lumina Research · 亮眼科学 Nature Author Correction: The genomic landscape of response to EGFR blockade in colorectal cancer 对此前发表的结直肠癌 EGFR 阻断治疗基因组景观研究的作者更正。原始研究系统描绘了 EGFR 阻断治疗响应的基因组特征。 🔗 Nature Nature Immunology Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses Patin 团队建立了可挖掘的资源数据库,用于识别影响人类抗病毒抗体库表位特异性的人口统计学和遗传因素。对疫苗设计和个体化免疫策略具有重要参考价值。
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